Why the study?
Does exercise training for 15 weeks alter the intrinsic rate of contraction and cholinergic sensitivity in isolated atria from male rats?
Population
Isolated atria from male rats
Comparison
Exercise training for 15 weeks vs Sedentary controls
Design
Preclinical
Follow-up
15 weeks
Authors
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Does not inform human practice; hypothesis-generating for intrinsic and parasympathetic mechanisms of exercise bradycardia in rodents.
Does exercise training for 15 weeks alter the intrinsic rate of contraction and cholinergic sensitivity in isolated atria from male rats?
Exercise-induced bradycardia in rats involves both a decrease in the intrinsic rate of the sinoatrial node and an increase in cardiac parasympathetic activity.
Bolter et al. (1973) studied this question.
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