Why the study?
Does the dose of propofol affect haemodynamic disturbances during induction of anaesthesia in children?
Population
216 children (ASA 1)
Comparison
Propofol at doses from 1.6 mg/kg to 2.6 mg/kg in… vs Different doses of propofol compared against…
Design
RCT, randomly allocated to receive one of six different doses
Follow-up
5 minutes
Authors
Loading...
No dose adjustment within 1.6-2.6 mg/kg mitigates hemodynamic effects during pediatric propofol induction; confirms absence of dose-response relationship.
Does the dose of propofol affect haemodynamic disturbances during induction of anaesthesia in children?
Haemodynamic disturbances after induction of anaesthesia with propofol in children are not dose-related within the 1.6 to 2.6 mg/kg range.
SHORT et al. (1991) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: