Key result
Non-alcoholic fatty liver disease is independently associated with an increased risk of atrial fibrillation, a prolonged QTc interval, and bundle branch and atrioventricular blocks.
Why the study?
Recent studies have evaluated the relationship associating NAFLD with several ECG findings, but the results have been inconsistent.
Does non-alcoholic fatty liver disease increase the risk of cardiac arrhythmias and electrocardiogram modifications in adult individuals?
Systematic Review (n=401,745)
Does non-alcoholic fatty liver disease increase the risk of cardiac arrhythmias and electrocardiogram modifications in adult individuals?
NAFLD is independently associated with an increased risk of atrial fibrillation, prolonged QTc interval, and cardiac conduction abnormalities, suggesting a need for cardiovascular risk stratification in these patients.
May warrant ECG monitoring in NAFLD; leaves open whether screening improves outcomes.
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Ismaiel et al. (2019) conducted a systematic review in Non-Alcoholic Fatty Liver Disease (NAFLD) (n=401,745). Non-Alcoholic Fatty Liver Disease (NAFLD) vs. Individuals without NAFLD was evaluated on Cardiac arrhythmias and electrocardiogram modifications (atrial fibrillation, prolonged QTc interval, conduction abnormalities). Non-alcoholic fatty liver disease is independently associated with an increased risk of atrial fibrillation, a prolonged QTc interval, and bundle branch and atrioventricular blocks.
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