Why the study?
Does intra-arterial phentolamine reduce resistance in collateral arteries in patients with occlusion of the superficial femoral artery?
Population
5 patients with occlusion of the superficial femoral artery
Comparison
Intra-arterial phentolamine vs Baseline measurements without alpha-receptor…
Design
Case_series
Authors
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Supports sympathetic mediation of collaterals in SFA occlusion; hypothesis-generating, should not change practice without controlled trials.
Does intra-arterial phentolamine reduce resistance in collateral arteries in patients with occlusion of the superficial femoral artery?
Intra-arterial phentolamine reduces collateral resistance and blocks tilt-induced constriction, indicating sympathetic adrenergic mediation of collateral artery constriction in superficial femoral artery occlusion.
Agerskov et al. (1981) studied this question.
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