Population
Isolated rat portal vein
Comparison
Variations in external K+ and Ca2+ concentrations vs Normal Krebs solution
Design
Preclinical
Authors
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Animal data confirm calcium's role in rodent vascular smooth muscle; leaves open translation to human cardiovascular therapies.
Calcium is essential for the contractile mechanism and spontaneous spike discharge in the rat portal vein.
Axelsson et al. (1967) studied this question.
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