February 1, 1973Circulation Research

Dependency of Pial Arterial and Arteriolar Diameter on Perivascular Osmolarity in the Cat

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Why the study?

Does altering perivascular osmolarity affect the diameter of pial arteries in cats?

Population

Cats (pial arteries)

Comparison

Alteration of perivascular osmolarity using… vs Baseline osmolarity (317 mosmoles/liter)

Design

Preclinical

Authors

MWMichael WahlTrier University of Applied Sciences WKWolfgang KuschinskyUniversity of Bonn OBO. BosseLund University

Discussion

Member takes

Implication

Alters pial artery tone in feline models; leaves open relevance to human cerebral autoregulation.

Structured PICO

Does altering perivascular osmolarity affect the diameter of pial arteries in cats?

Population

Cats (pial arteries)

Intervention

Alteration of perivascular osmolarity (251 to 360 mosmoles/liter) using mannitol or NaCl via microapplication

Comparator

Baseline osmolarity (317 mosmoles/liter)

Outcome

Pial arterial and arteriolar diametersurrogate

Local changes in perivascular osmolarity can directly influence the resistance and diameter of pial arteries.

Cite This Study

Wahl et al. (1973) studied this question.

synapsesocial.com/papers/6a8987a8176d2ac34cfba51c https://doi.org/10.1161/01.res.32.2.162

View Full Paper

Ask AI

Bookmark

Dependency of Pial Arterial and Arteriolar Diameter on Perivascular Osmolarity in the Cat

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Dependency of Pial Arterial and Arteriolar Diameter on Perivascular Osmolarity in the Cat

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider