Why the study?
Does primary autonomic failure affect QT interval and QT dispersion compared to normal controls?
Population
53 participants, comprising 32 patients with chronic primary autonomic failure and 21 normal controls…
Comparison
Chronic primary (idiopathic) autonomic failure vs Normal controls without symptoms of ischaemic…
Design
Case-control
Authors
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QT prolongation in autonomic failure may warrant monitoring; leaves open autonomic modulation of repolarization risk.
Does primary autonomic failure affect QT interval and QT dispersion compared to normal controls?
Primary autonomic failure is associated with prolonged QT intervals but not altered QT dispersion, suggesting the autonomic nervous system is an important determinant of QT duration.
Lo et al. (1996) studied this question.
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