Familial amyloidotic polyneuropathy (FAP) = cardiac and circulatory function during anesthesia for liver transplantation

27 patients with Familial amyloidotic polyneuropathy (FAP) type I (TTR Met30) undergoing liver transplantation. Mean duration of disease 5 years, mean modified BMI 690. Pretransplant evaluation showed 6 patients with AV-conduction disturbances, 13 with echocardiographic signs of amyloid deposits, 5 with orthostatic reactions, and 2 with permanent pacemakers.

Liver transplantation (anesthesia and operation)

Hemodynamic instability during the preanhepatic phase and actuarial 1- and 2-year survivalhard clinical