Why the study?
How does oral cadralazine affect carotid and brachial artery hemodynamics in normal versus hypertensive subjects?
Population
19 subjects (9 normal subjects and 10 subjects with sustained essential hypertension)
Comparison
Oral administration of cadralazine vs Baseline and comparison between normotensive and…
Design
Other
Follow-up
Immediate succession (acute)
Authors
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May indicate hypertension-specific carotid responses to vasodilation; leaves open baroreflex resetting effects.
How does oral cadralazine affect carotid and brachial artery hemodynamics in normal versus hypertensive subjects?
The carotid artery exhibits intrinsic wall alterations in essential hypertension, responding differently to vasodilation compared to the brachial artery, which may influence baroreceptor reflex resetting.
Laurent et al. (1988) studied this question.
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