Population
65-year-old woman with liver cirrhosis complicated by hepatocellular carcinoma, with no prior history of…
Design
Case_report
Follow-up
10 days to onset of symptoms
Authors
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May warrant caution with terfenadine in cirrhosis; leaves open need for confirmatory studies before practice change.
Terfenadine can induce torsades de pointes in patients with liver cirrhosis due to impaired hepatic metabolism, indicating it should be avoided in this population.
Kamisako et al. (1995) studied this question.
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