Why the study?
Does rimantadine inhibit influenza virus replication in MDCK cells?
Does rimantadine inhibit influenza virus replication in MDCK cells?
Rimantadine inhibits influenza virus replication in vitro by blocking early viral RNA polymerase activity formation when added immediately post-infection.
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May inform rimantadine antiviral mechanisms; leaves open translation from MDCK in vitro data to clinical use.
Koff et al. (1979) studied this question.
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