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January 1, 1984Journal of Medical Virology

Genome variants of adenovirus 41 (subgroup G) from children with diarrhoea in South Africa

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Population

15 strains of faecal adenovirus from children with diarrhoea

Design

Preclinical

Authors

AKAlistair H. KiddCentre National de la Recherche Scientifique

Discussion

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Overview

South African Ad41 strains show greater genomic diversity than European/Canadian isolates; leaves open implications for regional diagnostics and global surveillance.

Structured PICO

P
Population
15 strains of faecal adenovirus from children with diarrhoea (4 from Europe, 4 from Canada, and 7 from South Africa)
I
Intervention
Restriction enzyme analysis of DNA using Sma I and 9 other restriction enzymes
O
Outcome
Identification of genome types based on restriction enzyme cleavage sitessurrogate

The study identifies multiple distinct genome types of adenovirus 41 in South African children compared to European and Canadian strains.

Cite This Study

Alistair H. Kidd (1984) studied this question.

synapsesocial.com/papers/6a8a50d0788d49930fcbf987https://doi.org/10.1002/jmv.1890140108
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Antibodies to fastidious faecal adenoviruses (species 40 and 41) in sera from children1983 · 63 citations
  2. 2Molecular epidemiology of adenoviruses: alternating appearance of two different genome types of adenovirus 7 during epidemic outbreaks in Europe from 1958 to 19801981 · 59 citations
  3. 3Nucleotide sequences from the adenovirus-2 genome.1982 · 327 citations
  4. 4Faecal adenoviruses from Glasgow babies Studies on culture and identity1982 · 54 citations
  5. 5Restriction endonucleases in identification of a genome type of adenovirus 19 associated with keratoconjunctivitis1980 · 104 citations