Population
10 trileaflet heart valve scaffolds seeded with vascular cells from an ovine carotid artery
Design
Preclinical
Follow-up
4 days
Authors
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PHA scaffolds enable in vitro trileaflet valve function; leaves open in vivo durability and clinical translation.
Polyhydroxyalkanoates (PHAs) can be used to fabricate a three-dimensional, biodegradable trileaflet heart valve scaffold that supports cell attachment and mechanical function without the need for suturing.
Sodian et al. (2000) studied this question.
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