Key result
Stereolithography enabled the fabrication of anatomically accurate polymeric heart valve scaffolds that opened and closed synchronously in a pulsatile bioreactor.
Population
In vitro models of human pulmonary and aortic homografts derived from x-ray computed tomography data
Design
Preclinical
Authors
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May enable patient-specific valve scaffolds; leaves open durability and clinical translation.
Rapid prototyping using stereolithography and CT data can successfully fabricate anatomically accurate, functional polymeric scaffolds for tissue-engineered heart valves without the need for suturing.
Sodian et al. (2002) studied Tissue engineered heart valves. Stereolithography-derived heart valve scaffolds was evaluated on Functional testing in a pulsatile bioreactor. Stereolithography enabled the fabrication of anatomically accurate polymeric heart valve scaffolds that opened and closed synchronously in a pulsatile bioreactor.
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