Why the study?
The review evaluates the diagnostic and prognostic role of cardiotrophin-1 in patients with acute and chronic heart failure and its regulatory effects on cardiovascular remodeling.
Does monitoring cardiotrophin-1 provide diagnostic and prognostic value in patients with heart failure?
Does monitoring cardiotrophin-1 provide diagnostic and prognostic value in patients with heart failure?
Cardiotrophin-1 may serve as a useful biomarker for assessing cardiovascular remodeling and individualizing risk in patients with heart failure.
The review is devoted to the diagnostic and prognostic role of cardiotrophin-1 (CT-1) in patients with acute and chronic heart failure (CHF). The article provides information on the main regulatory effect of CT-1 in relation to the processes of cardiovascular remodeling. We considered the prospects of monitoring the plasma concentration of CT-1for the individualization of the assessment of cardiovascular risk in patients with CHF at various stages of the cardiovascular continuum. MeSH words: heart failure, cardiotrophin-1, hypertrophy, fibrosis, cytokines.
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Tokmachev et al. (2021) studied this question.
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