Population
Isolated perfused rat liver and kidney models
Comparison
Alterations in sodium balance and renal artery… vs Normal sodium balance and intact unclipped kidneys
Design
Preclinical
Authors
Loading...
Sodium balance may modulate renal angiotensin inactivation in animal models; leaves open translation to human hypertension.
Renal inactivation of angiotensin II is modulated by sodium balance and renal artery hemodynamics, whereas hepatic inactivation is independent of sodium balance.
Leary et al. (1970) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: