Population
Spleen cells from chickens 7 days after inoculation with Marek's disease virus, syngeneic normal spleen…
Comparison
Addition of MDV spleen cells to normal spleen… vs Normal spleen cells alone or MSB-1 cells alone
Design
Preclinical
Authors
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Hypothesis-generating for MDV-induced immunosuppression in chickens; leaves open relevance to human viral lymphoproliferative disease.
Macrophages from chickens inoculated with Marek's disease virus suppress mitogen-induced proliferation of normal spleen cells and DNA synthesis in lymphoblastoid cells.
Lee et al. (1978) studied this question.
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