Why the study?
Does early alcohol withdrawal increase urinary excretion of thromboxane metabolites in alcoholics compared to healthy controls?
Population
6 alcoholics undergoing alcohol withdrawal and 6 non-alcoholic healthy volunteers
Comparison
Early alcohol withdrawal (observational) vs Non-alcoholic healthy volunteers
Design
Case-control
Follow-up
14 days
Authors
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Early alcohol withdrawal associates with higher thromboxane metabolites in alcoholics; leaves open links to thrombotic risk and need for prospective studies.
Does early alcohol withdrawal increase urinary excretion of thromboxane metabolites in alcoholics compared to healthy controls?
Early alcohol withdrawal is associated with increased thromboxane A2 biosynthesis and reduced platelet count, suggesting platelets as the cellular origin of the increased TxA2 formation.
Neiman et al. (1994) studied this question.
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