Why the study?
Does alcohol withdrawal alter platelet count and function in alcoholics?
Population
24 alcoholics admitted for alcohol withdrawal, with measurable blood alcohol concentrations on admission.
Comparison
Supervised alcohol withdrawal and abstinence… vs Normal hospital personnel controls and baseline…
Design
Cohort
Follow-up
4 weeks
Authors
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May heighten post-withdrawal thromboembolic risk in alcoholics; hypothesis-generating and should not yet change practice.
Does alcohol withdrawal alter platelet count and function in alcoholics?
Alcohol withdrawal induces a transient but significant state of platelet hyperaggregability and activation that peaks at 1-2 weeks, which may contribute to the increased risk of thromboembolic events observed in heavy drinkers.
Fink et al. (1983) studied this question.
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