March 1, 1970Archives of Internal Medicine

Alcoholic Thrombocytopenia in Three Inpatient Drinking Alcoholics

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Why the study?

Does alcohol consumption reduce platelet counts in alcoholics?

Population

3 known alcoholics without medical complications

Design

Case_series

Authors

RRRalph S. RybackTexas Biomedical Research Institute

Discussion

Member takes

Implication

May support direct alcohol effect on platelets in alcoholics; hypothesis-generating and requires confirmation beyond this single case.

Structured PICO

Does alcohol consumption reduce platelet counts in alcoholics?

Population

3 known alcoholics without medical complications (no evidence of liver disease, folate deficiency, or intravascular coagulation)

Intervention

Alcohol ad lib

Outcome

Platelet countsurrogate

Alcohol appears to have a direct effect on platelet turnover, causing thrombocytopenia in alcoholics independent of liver disease or folate deficiency.

Cite This Study

Ralph S. Ryback (1970) studied this question.

synapsesocial.com/papers/6a836f9d757fb0fdf6a9b648 https://doi.org/10.1001/archinte.1970.00310030085009

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Alcoholic Thrombocytopenia in Three Inpatient Drinking Alcoholics

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Alcoholic Thrombocytopenia in Three Inpatient Drinking Alcoholics

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider