July 1, 1971Acta Neurologica Scandinavica

Measles Antibodies Detected With Various Techniques in Sera of Patients With Multiple Sclerois

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Why the study?

Are measles antibody titers higher in patients with multiple sclerosis compared to matched controls?

Population

137 patients with multiple sclerosis and 137 controls matched by date of birth and place of residence

Design

Case-control

Authors

MPM. PaneliusTurku University Hospital ASA. SalmiMuscat College PHP. HalonenSigmund Freud Privatuniversität Wien

Discussion

Member takes

Implication

Leaves open possible measles-MS link; hypothesis-generating and should not alter management or diagnostics.

Structured PICO

Are measles antibody titers higher in patients with multiple sclerosis compared to matched controls?

Population

137 patients with multiple sclerosis and 137 controls matched by date of birth and place of residence

Comparator

137 controls matched by date of birth and place of residence

Outcome

Hemagglutination inhibition (HI) antibody titers to measles, rubella, mumps, and La Crosse virussurrogate

Patients with multiple sclerosis have significantly higher measles antibody titers compared to matched controls, suggesting a potential link between measles virus and MS etiopathogenesis.

Cite This Study

Panelius et al. (1971) studied this question.

synapsesocial.com/papers/6a8aedafeada60f85de3aa8f https://doi.org/10.1111/j.1600-0404.1971.tb07486.x

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Measles Antibodies Detected With Various Techniques in Sera of Patients With Multiple Sclerois

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Measles Antibodies Detected With Various Techniques in Sera of Patients With Multiple Sclerois

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider