Why the study?
Does human atrial natriuretic peptide infusion affect blood pressure in patients with essential hypertension?
Population
3 patients with essential hypertension
Design
Case_series
Follow-up
4 hours
Authors
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Caution with prolonged ANP infusion in sodium-depleted hypertensive patients; case report leaves open need for controlled trials.
Does human atrial natriuretic peptide infusion affect blood pressure in patients with essential hypertension?
Prolonged infusion of human atrial natriuretic peptide can cause symptomatic hypotension, an effect that is enhanced by sodium depletion in patients with essential hypertension.
Janssen et al. (1986) studied this question.
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