Why the study?
Does continuous mini-infusion of bupivacaine into the epidural space result in safe maternal and fetal blood concentrations in healthy women during labor?
Population
16 healthy women during labor
Design
Cohort
Follow-up
until delivery
Authors
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Supports safe epidural mini-infusion in labor; leaves open need for randomized trials before practice change.
Does continuous mini-infusion of bupivacaine into the epidural space result in safe maternal and fetal blood concentrations in healthy women during labor?
Continuous epidural mini-infusion of bupivacaine during labor maintains low, stable blood concentrations and appears safe for both mother and fetus.
Matouskova et al. (1979) studied this question.
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