Why the study?
Does prosthetic replacement of mitral or mitral and aortic valves improve clinical and haemodynamic outcomes in patients with valvular heart disease?
Does prosthetic replacement of mitral or mitral and aortic valves improve clinical and haemodynamic outcomes in patients with valvular heart disease?
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Prosthetic replacement of mitral and aortic valves significantly improves functional capacity and pulmonary pressures, although complete normalization of haemodynamics is rarely achieved.
A clinical and haemodynamic follow-up study was performed on 27 patients after cardiac operations with insertion of prosthetic mitral or mitral and aortic valves. The functional capacity improved postoperatively in 25 patients. The pulmonary wedge position and pulmonary artery pressures at rest were significantly reduced postoperatively, just as the pulmonary artery pressure during exercise was significantly lower at the follow-up. The postoperative heart size was also smaller, whereas cardiac index and pulmonary vascular resistance did not show any significant changes. Only a few of the patients obtained complete normalization of the haemodynamic variables. Possible reasons for this result are discussed.
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Uhrenholdt et al. (1973) studied this question.
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