Why the study?
Does rapid decline in residual renal function increase the risk of mortality and anuria in peritoneal dialysis patients?
Population
581 subjects on peritoneal dialysis with longitudinal prevalent data
Comparison
Rapid residual renal function decline vs Slower RRF decline
Design
Cohort
Key result
Rapid decline in residual renal function (≥ 0.09 decline) over 12 months was associated with an increased risk of death (HR 2.60; 95% CI 1.66-4.07) and anuria.
Authors
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Identifies rapid residual renal function loss as a high-risk marker in peritoneal dialysis;.
Cohort (n=581)
Does rapid decline in residual renal function increase the risk of mortality and anuria in peritoneal dialysis patients?
Hazard Ratio: 2.6 (95% CI 1.66–4.07)
Rapid decline in residual renal function over 12 months in peritoneal dialysis patients is strongly associated with increased risks of mortality and anuria, particularly in those with diabetes.
Hu et al. (2017) conducted a cohort in peritoneal dialysis (n=581). Rapid decline in residual renal function (≥ 0.09 decline) vs. < 0.09 decline in residual renal function was evaluated on death (HR 2.60, 95% CI 1.66 - 4.07). Rapid decline in residual renal function (≥ 0.09 decline) over 12 months was associated with an increased risk of death (HR 2.60; 95% CI 1.66-4.07) and anuria.
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