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February 1, 2015MedicineOpen Access

There were significant differences in the 1-year changes in LVEDVI, LAVI, and LVMI between the faster and slower RRF decline groups (P = 0.047, 0.048, and 0.001, respectively), with indices decreasing only in the slower decline group.

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Why the study?

Does a faster rate of residual renal function decline worsen echocardiographic parameters and clinical outcomes in incident peritoneal dialysis patients?

Population

81 incident peritoneal dialysis patients who underwent baseline and follow-up echocardiography within the…

Comparison

Faster residual renal function decline vs Slower residual renal function decline

Design

Cohort

Follow-up

mean 31.9 months

Authors

HKHyang Mo KooFDFa Mee DohCKChan Ho Kim

Discussion

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Overview

Slower RRF decline was associated with favorable LV remodeling in incident PD; hypothesis-generating, prospective trials needed before practice change.

Structured PICO

Does a faster rate of residual renal function decline worsen echocardiographic parameters and clinical outcomes in incident peritoneal dialysis patients?

P
Population
81 incident peritoneal dialysis (PD) patients who underwent baseline and follow-up echocardiography within the first year of PD at a single center in South Korea.
I
Intervention
Faster residual renal function (RRF) decline (slope < -1.60 mL/min/y/1.73 m²)
C
Comparator
Slower residual renal function (RRF) decline (slope ≥ -1.60 mL/min/y/1.73 m²)
O
Outcome
1-year changes in echocardiographic parameters (LV end-diastolic volume index [LVEDVI], left atrial volume index [LAVI], and LV mass index [LVMI])surrogate

Preservation of residual renal function in incident peritoneal dialysis patients is associated with improved cardiac structural parameters and better clinical outcomes.

Cite This Study

Koo et al. (2015) studied this question.

synapsesocial.com/papers/6a7df0867c193befc433a5cfhttps://doi.org/10.1097/md.0000000000000427
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Fast Decline of Residual Renal Function in the First Year is a Predictor for Early Withdrawal from Peritoneal Dialysis in Non-Diabetic Patients2019 · 10 citations
  2. 2The Effect of Preserved Residual Renal Function on Left Ventricular Structure in Non-Anuric Peritoneal Dialysis Patients2015 · 14 citations
  3. 3#2752 Decline of residual renal function in peritoneal patients: in search of the lost kidney?2024
  4. 4Baseline and Time‐Averaged Values Predicting Residual Renal Function Decline Rate in Japanese Peritoneal Dialysis Patients2017 · 11 citations
  5. 5Rapid Change in Residual Renal Function Decline is Associated with Lower Survival and Worse Residual Renal Function Preservation in Peritoneal Dialysis Patients2017 · 18 citations