Population
109 patients with transplanted human hearts (n=283 biopsies) with and without microvascular fibrin.
Design
Cross-sectional
Authors
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VEGF links to thrombosis and inflammation in allografts; hypothesis-generating for endothelial activation in rejection, requires longitudinal validation before clinical use.
Endogenous VEGF is expressed locally following vascular thrombosis and myocardial cell damage in transplanted human hearts, potentially relating to endothelial cell activation.
Torry et al. (1995) studied this question.
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