Population
Rat aortic and small mesenteric artery rings
Comparison
Ouabain at various concentrations, with or… vs Control conditions (no ouabain)
Design
Preclinical
Authors
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May modulate rat arterial tone at nanomolar levels; leaves open human relevance for endogenous ouabain or digitalis.
Nanomolar concentrations of ouabain augment caffeine-evoked contractions in rat arteries, indicating that low levels of ouabain can influence vascular responsiveness to vasoconstrictors.
Weiss et al. (1993) studied this question.
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