Why the study?
Does propranolol reduce blood pressure in hypertensive outpatients?
Population
24 carefully selected hypertensive outpatients
Comparison
Propranolol 60 mg/day, 120 mg/day, and 240… vs Placebo for four weeks
Design
RCT, randomised sequence, double-blind
Follow-up
four weeks each
Authors
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Propranolol 120-240 mg/day lowers BP in hypertensive outpatients; confirms efficacy with dose plateau above 60 mg in RCT.
Does propranolol reduce blood pressure in hypertensive outpatients?
Propranolol at doses of 120 mg/day and 240 mg/day effectively reduces blood pressure in hypertensive outpatients, with 120 mg/day being as effective as 240 mg/day.
Galloway et al. (1976) studied this question.
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