Why the study?
Is the angiotensinogen gene linked to the pathogenesis of essential hypertension in Chinese populations?
Population
310 hypertensive sibling pairs of Chinese ethnicity
Design
Other
Authors
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Population differences may preclude angiotensinogen linkage in Chinese hypertension; challenges prior ethnic associations and leaves open other genetic mechanisms.
Is the angiotensinogen gene linked to the pathogenesis of essential hypertension in Chinese populations?
Unlike in White European, African-Caribbean, and Japanese populations, the angiotensinogen gene does not appear to be linked to essential hypertension in Chinese populations.
Niu et al. (1998) studied this question.
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