October 4, 2016EP EuropaceOpen Access

Patterns of physical activity and survival following cardiac resynchronization therapy implantation: the ALTITUDE activity study

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Why the study?

Does an increase in device-measured physical activity following CRT-D implantation predict improved survival?

Structured PICO

Does an increase in device-measured physical activity following CRT-D implantation predict improved survival?

Population

26,509 patients entered into the LATITUDE remote monitoring system from 2008 to 2012 after receipt of a new cardiac resynchronization therapy with implantable defibrillator backup (CRT-D), mean age 70.2, 70.7% male.

Intervention

Higher device-measured physical activity change between baseline (first 3-10 days) and 6 months (180-210 days) following CRT-D implantation

Comparator

Lower physical activity change (lowest quintile of baseline-6-month activity change)

Outcome

Survival (risk of death) at median 2.3 years follow-uphard clinical

An increase in device-measured physical activity at 6 months post-CRT implantation is strongly associated with improved long-term survival.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Supports device activity monitoring for post-CRT-D prognosis; leaves open whether increasing activity improves outcomes.

Cite This Study

Kramer et al. (2016) studied this question.

synapsesocial.com/papers/6a8bd95a95f0361a9ebee78d https://doi.org/10.1093/europace/euw267

Topics

Heart failure HFrEF treatment

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Patterns of physical activity and survival following cardiac resynchronization therapy implantation: the ALTITUDE activity study

Structured PICO

Discussion

Implication

Cite This Study

Topics

Patterns of physical activity and survival following cardiac resynchronization therapy implantation: the ALTITUDE activity study

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider