Population
Excised blocks of dog left ventricular walls
Comparison
10% stretching of the tissue from its unloaded… vs Unloaded state
Design
Preclinical
Authors
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May increase coronary resistance assessment caution at low pressures; leaves open translation from animal stretch models to human physiology.
Mechanical interaction between a coronary artery and surrounding tissue, affecting hydraulic resistance, depends on both transmural pressure and the direction of stretching.
Sipkema et al. (1996) studied this question.
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