Population
Vascular smooth muscle cell lines derived from aortae of spontaneously hypertensive rats and normotensive…
Comparison
Stimulation with angiotensin II and endothelin-1 vs Normotensive control cells and unstimulated cells
Design
Preclinical
Authors
Loading...
Supports angiotensin II-driven mitogenesis in hypertensive vascular cells; leaves open phospholipase D as a human therapeutic target.
Angiotensin II stimulates mitogenesis in vascular smooth muscle cells from spontaneously hypertensive rats, partially through the phospholipase D pathway.
Morton et al. (1995) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: