Population
Rats with congestive heart failure induced by ligation of the left coronary artery, and Sham-operated…
Comparison
In vitro assessment of isolated mesenteric… vs Arteries from Sham-operated control rats.
Design
Preclinical
Authors
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Attenuated alpha-adrenoceptor responses in rat CHF arteries warrant clinical caution; hypothesis-generating for human vascular mechanisms.
Resistance arteries from rats with congestive heart failure exhibit attenuated alpha-adrenoceptor responses and altered Ca2+-mediated vascular contractility.
Bergdahl et al. (2001) studied this question.
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