Why the study?
Does phytohemagglutinin stimulation activate measles virus in silently infected human lymphocytes?
Population
Human lymphocytes silently infected with measles virus
Comparison
Stimulation with phytohemagglutinin (PHA) vs Nonstimulated lymphocytes
Design
Preclinical
Follow-up
Up to 72 hours post-stimulation
Authors
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Animal data suggest latent measles inducibility by PHA; leaves open human relevance and clinical reactivation.
Does phytohemagglutinin stimulation activate measles virus in silently infected human lymphocytes?
This study demonstrates that silently infected human lymphocytes can be induced to produce active measles virus upon stimulation with phytohemagglutinin.
Lucas et al. (1978) studied this question.
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