Population
Lymphocytes from measles-seropositive individuals with prior histories of measles, seronegative individuals…
Comparison
In vitro lymphocyte-mediated cytotoxicity assay… vs Lymphocytes from seronegative individuals and…
Design
Preclinical
Authors
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Assay detects measles-specific cell-mediated immunity in seropositive individuals with disease history; leaves open validation for SSPE risk assessment.
The described in vitro assay successfully measures measles-specific cell-mediated immunity, which may help evaluate normal hosts and those predisposed to subacute sclerosing panencephalitis.
Labowskie et al. (1974) studied this question.
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