Population
Rats congenic for the chromosome 1 quantitative trait locus region and Wistar-Kyoto/Izm rats
Comparison
Restraint stress vs WKY rats (control strain)
Design
Preclinical
Authors
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Rat model links chromosome 1 QTL to sympathetic stress BP responses; leaves open specific genes and human translation.
A gene or genes in the chromosome 1 QTL region modulates cardiovascular responses to restraint stress in rats, likely via the sympathetic nervous system.
Cui et al. (2003) studied this question.
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