Population
Congenic rat strain WKYpch1.0 (derived from SHRSP/Izm and WKY/Izm) and WKY rats
Comparison
Congenic strain WKYpch1.0 carrying SHRSP… vs Wistar-Kyoto (WKY) rats
Design
Preclinical
Follow-up
4 hours
Authors
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Supports rat chromosome 1 QTL in stress-induced sympathetic hyperactivity; leaves open translation to human hypertension.
The QTL region on rat chromosome 1 from SHRSP harbors genes responsible for an exaggerated sympathetic nervous system response to cold stress.
Cui et al. (2004) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: