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January 1, 2021TURKISH JOURNAL OF MEDICAL SCIENCESOpen Access

All 6 cases were discharged without sequelae after an average of 12.1 ± 7 days of hospitalization, with radiological recovery between 14 days and 2 months.

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Why the study?

Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a rare clinicoradiological syndrome presenting with central nervous system symptoms.

Population

6 pediatric patients with MERS

Design

Single-center case series

Authors

HÇHalil ÇeliEAErh AksoyÜÖÜlkühan Öztoprak

Discussion

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Overview

May support expectant management in MERS; leaves open need for prospective validation.

Structured PICO

P
Population
6 pediatric patients with mild encephalitis/encephalopathy with a reversible splenial lesion (MERS), mean age 122 ± 54.6 months, 3 boys and 3 girls, no chronic diseases.
O
Outcome
Clinical and MRI findings, hospitalization duration, and radiological recovery

MERS is an acute encephalopathy with a good prognosis, presenting with variable clinical symptoms and specific MRI findings, and typically resolves without sequelae.

Cite This Study

Çeli et al. (2021) studied this question.

synapsesocial.com/papers/6a8be79ef19228bbb2fb67b1https://doi.org/10.3906/sag-2110-73
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of thecorpus callosum in childhood: a single-center experience2022 · 2 citations
  2. 2Mild Encephalitis/Encephalopathy With a Reversible Splenial Lesion of the Corpus Callosum (MERS): A Report of Two Pediatric Cases2026
  3. 3Mild Encephalopathy With Reversible Splenium Lesion in Pediatric Patients2026
  4. 4Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS): A case report and review of the literature2026
  5. 5Mild Encephalopathy with Reversible Splenial Lesion in an Adult Patient with Atypical Presentation2025