Why the study?
Do plasma BNP and ANP concentrations correlate with right ventricular dysfunction in patients with chronic right ventricular pressure overload due to congenital heart disease?
Population
21 asymptomatic or minimally symptomatic patients with chronic right ventricular pressure overload caused by…
Comparison
Measurement of plasma brain natriuretic peptide… vs Healthy volunteers (n=7).
Design
Cross-sectional
Authors
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Supports biomarker monitoring of RV function; hypothesis-generating in congenital heart disease and requires prospective validation.
Do plasma BNP and ANP concentrations correlate with right ventricular dysfunction in patients with chronic right ventricular pressure overload due to congenital heart disease?
Plasma BNP and ANP levels inversely correlate with right ventricular ejection fraction, suggesting their utility in monitoring right ventricular dysfunction in patients with congenital heart disease and RV pressure overload.
Tulevski et al. (2001) studied this question.
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