Why the study?
Do humoral antibodies correlate with resistance to poliomyelitis reinfection in convalescent versus vaccinated monkeys?
Population
Monkeys convalescent from a paralytic attack of poliomyelitis and vaccinated monkeys
Comparison
Convalescence from paralytic attack of… vs Vaccination against poliomyelitis
Design
Preclinical
Follow-up
Up to 3 months
Authors
Loading...
Antibodies from vaccination may not confer nasal resistance in primate polio models; leaves open distinct convalescent mechanisms for human study.
Do humoral antibodies correlate with resistance to poliomyelitis reinfection in convalescent versus vaccinated monkeys?
Humoral antibodies do not have the same significance for resistance to poliomyelitis infection in vaccinated monkeys as they do in convalescent monkeys.
Sabin et al. (1936) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: