Population
9 open-chest anaesthetized dogs
Comparison
Maximal vasodilatation with adenosine vs Autoregulated coronary bed
Design
Preclinical
Authors
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Diastolic myocardial pressure may shape coronary zero-flow pressure during autoregulation; leaves open its relevance to human coronary physiology.
Diastolic myocardial tissue pressure, in addition to coronary vasomotor tone, is important in the genesis of coronary pressure at zero flow.
Sabbah et al. (1986) studied this question.