Why the study?
Does intravenous dantrolene reduce temperature and rigidity in hospitalized patients with refractory hyperthermic conditions?
Does intravenous dantrolene reduce temperature and rigidity in hospitalized patients with refractory hyperthermic conditions?
Intravenous dantrolene is associated with reductions in temperature and rigidity in patients with hyperthermia of diverse origins in intensive care settings.
May support dantrolene in MH/NMS; observational data leave open efficacy for other hyperthermias and require RCTs.
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Pawar et al. (2015) studied this question.
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