This case report highlights the potential for malignant fibrous histiocytoma to develop following radiation therapy for fibrous dysplasia.
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May warrant caution with radiation in fibrous dysplasia; case reports leave open the magnitude of risk.
Malignant fibrous histiocytoma commonly occurs spontaneously. In some cases it follows previous therapeutic or incidental irradiation, or miscellaneous pre-existing osseous conditions. Recently, it has been associated with total hip arthroplasty. We report a case of malignant fibrous histiocytoma following radiation therapy of fibrous dysplasia and review the relevant literature.
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Amin et al. (1995) studied this question.
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