Why the study?
Does combination antihypertensive therapy (verapamil/trandolapril or atenolol/nifedipine) affect glucose tolerance and insulin sensitivity in nonobese patients with essential hypertension?
Does combination antihypertensive therapy (verapamil/trandolapril or atenolol/nifedipine) affect glucose tolerance and insulin sensitivity in nonobese patients with essential hypertension?
Combination antihypertensive therapy effectively lowers blood pressure without adversely affecting glucose or lipid metabolism in nonobese, normolipidemic patients.
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Supports metabolic-neutral combinations in nonobese essential hypertension; confirms neutrality on glucose-insulin parameters in RCTs.
Quiñones-Galvan et al. (2002) studied this question.
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