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November 4, 2020Open Access

Outcome of pregnancies in pregnant women with pulmonary hypertension: a single-center experience from East China

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Key result

In pregnant women with pulmonary hypertension, overall maternal mortality was 3.0%, with significantly increased morbidity in those with pulmonary pressures ≥80 mmHg.

Why the study?

The study aimed to evaluate maternal and fetal outcomes in women with pulmonary hypertension resulting from different causes and to identify risk factors for adverse outcomes.

Population

603 pregnant women with pulmonary hypertension

Comparison

Outcomes compared across disease etiologies and pulmonary hypertension pressure levels

Design

Single-center observational study

Authors

HMHuixian MiaoShanghai Jiao Tong UniversityJLJianhua LinFujian Medical UniversityYCYunyan ChenHarbin Medical University

Discussion

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Implication

Supports individualized preconception counseling in pulmonary hypertension; extends observational risk estimates but leaves optimal interventions open.

Study Design

Type

Observational (n=603)

Multicenter

No

Structured PICO

P
Population
603 pregnant women with pulmonary hypertension, predominantly secondary to congenital heart disease, evaluated retrospectively for maternal and fetal outcomes.
O
Outcome
Maternal and fetal outcomes including mortality, abortion rate, preterm birth, heart failure, and fetal growth restrictionhard clinical

Pregnancy in women with pulmonary hypertension carries a 3.0% mortality rate, which is lower than previously reported but remains high in specific etiologies like Eisenmenger syndrome and with higher pulmonary pressures.

Cite This Study

Miao et al. (2020) conducted an observational in Pulmonary hypertension in pregnancy (n=603). Pulmonary hypertension was evaluated on Maternal mortality. In pregnant women with pulmonary hypertension, overall maternal mortality was 3.0%, with significantly increased morbidity in those with pulmonary pressures ≥80 mmHg.

synapsesocial.com/papers/6a8c3380bb5c03e832c463f3https://doi.org/10.22541/au.160452542.24516030/v1
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