Some Studies in the Mechanism of Cardiac Hypertrophy

Article1 November 1939SOME STUDIES IN THE MECHANISM OF CARDIAC HYPERTROPHYGEORGE HERRMANN, M.D., F.A.C.P., GEORGE M. DECHERD JR., M.D., F.A.CP.GEORGE HERRMANN, M.D., F.A.C.P.Search for more papers by this author, GEORGE M. DECHERD JR., M.D., F.A.CP.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-13-5-794 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHypertrophy of the heart is a reliable sign of heart disease. A definitely enlarged heart is foredoomed to failure. The functional disadvantages of enlargement of the myocardial fibers have been stressed by Harrison, Ashman, et al.1and by Wearn, Roberts, et al.2Cardiologists have held that recognizable hypertrophy is always pathological, progressive, irreversible and eventually detrimental. The argument that heart muscle hypertrophy may be advantageous like that of skeletal muscle, as exemplified by the blacksmith's biceps, may be countered with the argument that Sandow was really muscle-bound. The bulging muscle makes a striking show, but the long sleek muscle strikes...Bibliography1. HARRISONASHMANLARSON TRRRM: Congestive heart failure: relation between thickness of cardiac muscle fiber and optimum rate of heart, Arch. Int. Med., 1932, xlix, 151. CrossrefGoogle Scholar2. WEARNROBERTSBADAL JTJTJJ: Capillary-muscle ratio in normal and hypertrophied human hearts, Proc. Soc. Exper. Biol. and Med., 1938, xxxviii, 322. Google Scholar3. CHRISTIAN HA: The use of digitalis other than in the treatment of cardiac decompensation, Jr. Am. Med. Assoc., 1933, c, 789. CrossrefGoogle Scholar4. CLOETTA M: The effect of digitalis upon the normal and pathologic heart, Arch. Exper. Path. and Pharm., 1908, lix, 209. CrossrefGoogle Scholar5. 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DAVISBLUMGART DHL: Cardiac hypertrophy: its relation to coronary arteriosclerosis and congestive heart failure, ANN. INT. MED., 1937, xi, 1024. LinkGoogle Scholar21. RYTAND DA: Renal factor in arterial hypertension with coarctation of the aorta, Jr Clin. Invest., 1938, xvii, 391. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Read at the New Orleans meeting of the American College of Physicians March 28, 1939.From the Department of Medicine, University of Texas Medical School.Aided by Grants Nos. 444 and 530 of the Committee on Scientific Research of the American Medical Association. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byStates of Altered Metabolism in Diseases of MuscleCardiac dilatation and hypertrophy 1 November 1939Volume 13, Issue 5Page: 794-806KeywordsCardiac hypertrophyCardiovascular therapyHeart failureMusclesMyocardiumSkeletal muscles ePublished: 1 December 2008 Issue Published: 1 November 1939 PDF downloadLoading ...