Why the study?
Does intrapericardial infusion of urokinase improve drainage of coagulated pericardial effusion in a patient with purulent pericarditis?
Does intrapericardial infusion of urokinase improve drainage of coagulated pericardial effusion in a patient with purulent pericarditis?
Intrapericardial infusion of urokinase is a safe and effective method for draining coagulated pericardial effusion in purulent pericarditis, potentially avoiding the need for surgical pericardiectomy.
May aid drainage in refractory purulent pericarditis; hypothesis-generating and requires prospective trials before clinical adoption.
Intrapleural fibrinolytic therapy has become commonpractice, but reports of intrapericardial use are quite limited. We report a case in whichtranscatheter infusion of urokinase successfully resulted in the drainage of coagulated pericardial effusion.
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Kamimura et al. (2002) studied this question.
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