September 3, 2011Journal of General Internal MedicineOpen Access

Symptoms of Anxiety and Cardiac Hospitalizations at 12 Months in Patients with Heart Failure

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Why the study?

Do symptoms of anxiety predict cardiac hospitalizations at 12 months in outpatients with heart failure?

Population

237 outpatients with heart failure, mean age 66.9, 21.5% female, from two teaching hospitals in The…

Comparison

Presence of symptoms of anxiety vs Absence of symptoms of anxiety

Design

Cohort

Follow-up

12 months

Authors

NDNikki L. DamenDutch Hospital Association APAline J. PelleUniversity of Florida BSBalázs SzabóGottsegen National Cardiovascular Center

Discussion

Member takes

Implication

Does not support using anxiety symptoms for cardiac hospitalization risk stratification in HF outpatients; leaves open effects on other outcomes.

Structured PICO

Do symptoms of anxiety predict cardiac hospitalizations at 12 months in outpatients with heart failure?

Population

237 outpatients with heart failure (LVEF ≤40%, NYHA class I-III, stable on oral medication), mean age 66.9, 21.5% female, from two teaching hospitals in The Netherlands.

Intervention

Presence of symptoms of anxiety (Hospital Anxiety and Depression Scale [HADS] anxiety subscale score ≥8)

Comparator

Absence of symptoms of anxiety (HADS anxiety subscale score ≤7)

Outcome

Cardiac hospitalizations at 12 months (defined as any planned or unplanned overnight stay in the cardiology clinic, including HF-related and non-HF-related cardiac admissions)hard clinical

In outpatients with heart failure, self-reported symptoms of anxiety do not independently predict cardiac hospitalizations at 12 months, whereas clinical indicators of disease severity such as NYHA class III do.

Limitations

Subclinical symptoms of anxiety and depression were assessed using self-report, and no information on an established clinical diagnosis of anxiety was collected.
The majority of patients included were classified as NYHA I/II, which hampers generalizability to the general HF population and to patients with more severe HF.
Information on hospitalizations was only collected from the hospitals in which patients were enrolled, potentially underestimating admissions from other centers.
The sample size was relatively small, which may have caused power problems.

Cite This Study

Damen et al. (2011) studied this question.

synapsesocial.com/papers/6a8c75d9e2daec1d82d3cb2a https://doi.org/10.1007/s11606-011-1843-1

Topics

Heart failure HFrEF treatment Heart failure hospitalization

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Implication

Does not support using anxiety symptoms for cardiac hospitalization risk stratification in HF outpatients; leaves open effects on other outcomes.

Symptoms of Anxiety and Cardiac Hospitalizations at 12 Months in Patients with Heart Failure

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Topics

Symptoms of Anxiety and Cardiac Hospitalizations at 12 Months in Patients with Heart Failure

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Topics

Also Consider