Why the study?
Does a thoracic epidural block followed by intravenous prenalterol improve cardiovascular hemodynamics during infrarenal aortic cross-clamping in patients undergoing abdominal aortic resection and grafting?
Population
16 patients scheduled for abdominal aortic resection and grafting
Comparison
Thoracic epidural block followed by intravenous… vs No specific treatment prior to general anaesthesia
Design
RCT, Randomly assigned to two groups
Follow-up
Perioperative (measured 30 s after cross-clamping)
Authors
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Supports thoracic epidural plus prenalterol pretreatment to stabilize hemodynamics during aortic cross-clamping; confirms RCT benefit in vascular anesthesia.
Does a thoracic epidural block followed by intravenous prenalterol improve cardiovascular hemodynamics during infrarenal aortic cross-clamping in patients undergoing abdominal aortic resection and grafting?
Pretreatment with a thoracic epidural block and intravenous prenalterol attenuates the increase in systemic vascular resistance and prevents the decrease in stroke volume and cardiac index during infrarenal aortic cross-clamping.
Reiz et al. (1979) studied this question.
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